Searchable abstracts of presentations at key conferences in endocrinology

ea0037ep694 | Pituitary: basic and neuroendocrinology | ECE2015

Single dose irradiation of GH3 cells increase GH and PRL secretion in vitro

Fratticci Amato , Rotondi Sandra , Modarelli Alessio , Bonfili Pierluigi , Cesare Ernesto Di , Alesse Edoardo , Jaffrain-Rea Marie-Lise

Radiotherapy (RT) may represent a useful tool in the treatment of GH-secreting tumours in the presence of a post-operative active disease and single dose stereotactic RT/gamma knife is the preferred option in most cases. The effects of RT on the control of hormone secretion are very slow and pharmacological treatment remains necessary for years. Some authors advocate withdrawal of somatostatin analogues (SSA) during RT, although the short-term effects of RT on hormone secretio...